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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKC
All Species:
28.18
Human Site:
S297
Identified Species:
47.69
UniProt:
Q9UQB9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQB9
NP_001015878.1
309
35591
S297
H
P
W
V
Q
A
H
S
R
R
V
L
P
P
C
Chimpanzee
Pan troglodytes
XP_001142357
309
35587
S297
H
P
W
V
Q
A
H
S
R
R
V
L
P
P
C
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
S459
H
P
W
V
Q
V
H
S
R
R
V
L
P
P
C
Dog
Lupus familis
XP_849906
346
39574
S333
H
P
W
V
R
A
H
S
R
R
M
L
P
P
S
Cat
Felis silvestris
Mouse
Mus musculus
O88445
282
32888
S270
H
P
W
V
R
E
H
S
R
R
V
L
P
P
C
Rat
Rattus norvegicus
O55099
343
39216
P328
L
E
Q
V
S
A
H
P
W
V
R
A
N
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
S286
H
P
W
I
T
A
N
S
S
K
A
P
N
S
L
Chicken
Gallus gallus
XP_425725
409
46456
P395
L
K
D
V
L
V
H
P
W
I
T
A
N
S
T
Frog
Xenopus laevis
Q6GPL3
368
41997
S354
H
P
W
V
K
A
N
S
R
R
V
L
P
P
V
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
S307
H
P
W
V
K
A
N
S
R
R
V
L
P
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
M309
H
Y
W
V
K
A
G
M
A
E
R
E
L
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
K292
E
A
K
I
R
A
E
K
Q
Q
K
I
E
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
W269
H
K
L
L
E
H
P
W
I
V
Q
N
A
D
P
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
P353
L
G
D
V
K
M
H
P
W
I
L
R
N
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.4
70.5
N.A.
72.4
67.3
N.A.
64.7
52.3
58.1
65.3
N.A.
43.1
N.A.
54.6
N.A.
Protein Similarity:
100
100
64.7
78.9
N.A.
82.5
79.3
N.A.
78.3
62.3
71.1
78.7
N.A.
62.6
N.A.
68.9
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
20
N.A.
33.3
13.3
80
80
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
20
N.A.
53.3
13.3
93.3
93.3
N.A.
33.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.3
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
65
0
0
8
0
8
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
8
0
0
8
8
8
0
0
8
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
72
0
0
0
0
8
58
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
0
0
8
15
0
8
0
0
0
% I
% Lys:
0
15
8
0
29
0
0
8
0
8
8
0
0
15
0
% K
% Leu:
22
0
8
8
8
0
0
0
0
0
8
50
8
0
15
% L
% Met:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
22
0
0
0
0
8
29
0
0
% N
% Pro:
0
58
0
0
0
0
8
22
0
0
0
8
50
50
15
% P
% Gln:
0
0
8
0
22
0
0
0
8
8
8
0
0
8
0
% Q
% Arg:
0
0
0
0
22
0
0
0
50
50
15
8
0
0
8
% R
% Ser:
0
0
0
0
8
0
0
58
8
0
0
0
0
22
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% T
% Val:
0
0
0
79
0
15
0
0
0
15
43
0
0
0
15
% V
% Trp:
0
0
65
0
0
0
0
8
22
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _